摘要
本文对比观察了静注心得安和垂体后叶素对人体门脉压的影响。对20例门脉高压症患者于切脾、断流术中采用了测定胃网膜右静脉压变化的方法进行观测,结果表明:静注垂体后叶素后胃网膜右静脉压及血压逐渐增高,少数病例可出现严重的心律失常;而静注心得安后胃网膜右静脉压显著下降。静注心得安使心率减慢24.1％,若出现重度的心动过缓,可静注阿托品纠正。心得安静注的有效剂量有个体差异,提示心得安降门脉压的效果优于垂体后叶素。
The Portal pressure of twenty patients with portal hypertension was studied by intravenous infu- sion of propranolol (10 cases) or vasopressin(10 cases) and determination of right gastroepipleic ve- nous pressure during splenectomy. The results showed that after infusion of vasopressin, the Peripher- al blood pressure and right gastroepiploic venous pressure increased gradually (4.96±1.27kPa,P<0. 001;0.64<0.65kPa, P<0.02),severe arrhythmia occurred in two cases. on the contrary, after in- travenous infusion of propranolol the right gastroepiploic venous pressure decreased obviously(0.85± 0.88kPa,P<0.005),and heart beat deccreased by 24.1%. If severebredycadia occurred in the lat- ter, it could be corrected by intravenous injection of atropin. The dosage of propranolol for decreasing portalpressure showed individual difference. It is suggested that intravenous infusion of propranolol was markely superior to that of vasopressin in lowering right gastroepiploic venous pressure.
出处
《江西医学院学报》
1990年第4期35-38,共4页
Acta Academiae Medicinae Jiangxi
关键词
门脉高压
心得安
垂体后叶素
静脉注射
食道静脉曲张
破裂出血
hypertension portal venous/drug therapy
drug evaluation/methods
propranolol/therapeutic use
Pituitary hormones
porterior/therapeutic use
hypertention
portal venous/surgery
comparative study
case report
