摘要
同源盒基因是一种成簇基因 ,作为胚胎发育的主控基因 ,不仅在胚胎发育、细胞生长、分化、迁移和某些组织特异性基因的表达中起重要作用 ,而且在造血组织发育和分化中以种系特异性和阶段特异性的方式起调控作用。目前研究表明同源盒基因与肿瘤的发生关系密切 ,本文主要综述同源盒基因的结构及其有关方面的研究进展。
As master genes during embryogenesis, Homeobox(Hox) genes play important roles not only in embryonic development, cellular growth and differentiation and the expression of the specific genes of some tissue, but also in controlling hematopoietic tissue development and differentiation in a germ line -specific and stage-specific. At present studies showed there is a close relationship between Hox genes and tumorgenesis. This article reviews the advances in the research on correlation between homeobox genes and tumorgenesis.
出处
《中国癌症杂志》
CAS
CSCD
2001年第6期558-561,共4页
China Oncology
