摘要
目的观察剖宫产术后经静脉镇痛对宫缩、泌乳及胎儿体重的影响.方法选择30例健康足月无妊娠合并症,并发症在硬膜外麻下行剖宫产产妇,术后自愿接受静脉镇痛为镇痛组,选择同期条件相同未行静脉镇痛的产妇30例为对照组.镇痛组在剖宫产术后,采用病人自控静脉镇痛(PCIA)给予芬太尼,芬太尼持续剂量20～25 μg/h,镇痛时间48 h,采用放射免疫法测血浆催乳素(PRL)浓度.结果镇痛组术后第1天PRL增高,显著高于对照组(P <0.05),镇痛组初乳时间较对照组提前(P<0.05),两组产后流血、宫缩、肠蠕动恢复时间,婴儿体重增减无显著性差异(P>0.05),但镇痛组术后出现呕吐的产妇高于对照组( P<0.01).结论剖宫产术后采用芬太尼PCIA,能使初乳时间及PRL分泌提前,不影响宫缩,对婴儿亦无不良影响.
ObjectiveTo observe the effects of intravenous analgesia on uterine contraction, colostrum secretion and infant weight after Cesarean section.MethodsSixty parturients were divided into two groups: (1) Intravenous analgesia (IA) group---Cesarean sections were performed under epidural anesthesia in 30 full term parturient who had no pregnancy-concurrent conditions and complications. They volunteered to receive IA after operation; (2) Control group---IA was not given after Cesarean section in other 30 parturients with the same conditions during the same period. In IA group, intravenous fentanyl was administered under self-control at the rate of 20～25 ug/h. Its analgesic action lasted 48 hours. Their plasma concentration of prolactin (PRL) was determined with radioimmunoassay (RIA). ResultsPlasma PRL levels in IA group increased on the first day after Cesarean section, significantly higher than those in control group (P<0.01); whereas their colostrum secretion was earlier than that in control group (P<0.05). No obvious differences in postpartum hemorrhage, uterine contraction, peristalsis resumption time and infant weights were found between two groups (P>0.05), but the incidence of vomiting after Cesarean section in IA group was higher than that in control group (P<0.01). ConclusionIA with fentanyl after Cesarean section makes colostrum and PRL secretion earlier, not affecting uterine contraction and infant weight.
作者
汪蓓
邹放军
朱定
Wang Bei, Zhou Fang jun, Zhu Ding (Hunan Provincial Hospital, Changsha 410002, China)
出处
《湖南医学》
2002年第1期6-7,共2页
Hunan Medical Journal
