3Pinzani M,Milani S,De-Franco R,et al.Endothelin 1 is overexpressed in human cirrhotic liver and exerts multiple effects onactivated hepatic stellate cells.Gastroenterology,1996,110:534
4Gallai M,Kovalszky I,Knittel T,et al.Expression of extra-cellular matrix proteoglycan sperlecan and decorin in carbon-tetra-chloride-injured rat liver and in isolated liver cells,Am J Path,1996,148:1463
5Gressner AM,Meyer D,Krull N,et al.Characterization of theexpression of the transcripts of small chondroitin/dermatern sulfateprteoglycans,biglycan and decorin in fibrotic rat livers and isolatedliver cells.Hepatol,1991,14:113A
6Arthur MJP.Fibrosis and altered matrix degradation.Digestion,1998,59:376
7Knittel T,Mehde M,Kobold D,et al.Expression patternsof matrix metelloproteinases and their inhibitors in parenchymaland non-parenchymal cells of rat liver,regulation by TNF-alfa andTGF beta 1.J Hepatol,1999,30:48
8Benyon RC,Iredale JP,Goddard S,et al.Expression oftissue inhibitor of metalloproteinase 1 and 2 is increased in fibrotic human liver.Gastroenterolagy,1996,110:821
9Herbst H,Wege T,Milani S,et al.Tissue inhibitor of metallo-proteinase-land -2 RNA expression in rat and human liver fibro-sis.Am J Pathol,1997,150:1647
10Knittel T,Fellmer P,Ramadori G.Gene expression andregulation of plasminogen activator inhibitor type I in hepatic stellate cells of rat liver.Gastroenterology,1996,111:745
2Walsh KM,Timms P,Campbell S.et al. Plasma levels of M MP-2 and TIMP-1 and TIMP-2 as noninvasive markers of liver disease in chronic hepatitis C :comparison using ROC analysis[J]. Dig Dis Sci,1999,44(3) :624.
3Ninoniya T, Yoon S, Hayashi Y.et al. Clinical significance of serum hyaluronic acid as a fibrosis marker in chronic C patient treated with interferon-alpha histological evaluation by a modified histology ic al activity index scoring system[J]. J Gastroenterol Hepatol,1998,13(1) :68.
4Kozlowska J, Loch T,Jablonska J, et al. Biochemical markers of fibrosis in chronic hepatitis and liver cirrhosis of viral origin[J].Przegl Eoidemiol.2001.55(3) :451.