摘要
目的 探讨国际常用的华盛顿医科大学生存质量 (universityofwashington QOL ,UW QOL)量表 ,在中国喉癌患者QOL研究中应用的可行性。方法 对 37例全喉切除和 81例喉部分切除的喉癌患者进行UW QOL量表问卷调查 ,比较喉全切除术和喉部分切除术后患者生存质量 (gualityoflife,QOL)的不同 ,分析喉癌患者术后影响生存质量的因素。结果 喉部分切除术组患者的QOL总分(6 92 .34± 12 7.94)高于喉全切除术组 (6 36 .35± 139.97,P <0 .0 5 ) ,说话交流和外貌方面 (74.32±2 3.82 ,80 .86± 2 0 .2 6 )显著高于喉全切除术组 (4 0 .2 7± 2 5 .76 ,6 9.5 9± 2 7.0 9;P <0 .0 0 1,P <0 .0 5 ) ;而后者在疼痛方面 (92 .5 7± 13.0 0 )要高于前者 (83.0 2± 2 0 .47;P <0 .0 1)。喉癌分期、术式、并发症、术后放化疗、与谁同住及手术前后有无慢性病是影响患者术后生存质量的因素。结论 喉部分切除术能提高喉癌患者术后整体生存质量 ,改善术后说话交流功能及外貌。UW QOL量表可用于中国喉癌患者生存质量研究。
Objective To assess the feasibility of University of Washington Quality of Life (UW-QOL) questionnaire in laryngeal cancer patients treated by total or partial laryngectomy and their prognostic factors in China. Methods With UW-QOL questionnaire, a survey was conducted in patients treated by partial (81, Group A) or total (37, Group B) laryngectomy for laryngeal cancer. Results The composite QOL scores of group A (692.34±127.94) were higher than those of group B (636.35±139.97), with a difference statistically significant ( P <0.05). Group A (74.32±23.82; 80.86±20.26) was better than group B (40.27±25.76; 69.59±27.09) in speech and appearance ( P <0.001; P <0.05); but group B (92.57±13.00) was superior to group A (83.02±20.47) in pain ( P <0.01). Six factors including stage, operative, modality, complication, postoperative radiotherapy or chemotherapy, with whom to live, chronic disease before or after operation were related to postlaryngectomy QOL. Conclusion Partial laryngectomy is superior to total laryngectomy in speech, appearance and overall QOL. UW-QOL questionnaire is suitable for QOL research in laryngeal cancer in China.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
2002年第1期53-56,共4页
Chinese Journal of Oncology
