摘要
现代发酵技术的首要条件是纯种培养和大规模集约化生产。固态发酵技术关键问题是缺乏符合现代工业要求的固态发酵反应器。压力脉动固态发酵反应器是一个对密闭低压容器内的气相压力施以周期脉动 ,使发酵料层内的气相传质由分子扩散变为强制对流扩散 ,解决了固态发酵传热、传质差和难于大规模纯种培养等问题。目前 ,压力脉动固态发酵反应器已成功地从实验室放大到工业级生产规模 ,应用范围涉及到抗生素、酶制剂、有机酸、食品添加剂。
The main conditions of modern fermentative technique are pure culture and large scale production The key problem faced by solid state fermentation is the lack of ripe solid state fermenter Large scale pure culture was accomplished in pressure pulsating solid state fermenter Air pressure pulsation in the fermenter can increase mass and heat transfers and improve the porosity within the substrate The new solid state fermentation technology can lower the construction investment, decrease the production cost, save energy consumption and be more favorable to environment This bioreactor is now being successfully scale up from lab scale to commercialized scale It application fields cover antibiotics,enzymes,organic acids,food additives,biofertilizers,etc
出处
《化工进展》
EI
CAS
CSCD
北大核心
2002年第1期37-39,共3页
Chemical Industry and Engineering Progress
关键词
固态发酵反应器
设计原理
纯种培养
大规模集约化
pressure pulsating solid state fermenter, design principle for bioreactor, large scale and pure culture
