摘要
目的 评估尿淀粉酶 /尿肌酐比值 (Uamy/Ucr)及尿胰蛋白酶原 2快速测定对急性胰腺炎的诊断价值。 方法 对 5 7例怀疑急性胰腺炎的急腹症患者进行血尿淀粉酶 (Amy)、尿肌酐 (Ucr)及尿胰蛋白酶原 2快速测定和B超检查。结果 5 7例中 18例确诊为急性胰腺炎 ,其余 39例则为其他原因导致的急腹症。血清Amy对急性胰腺炎的诊断敏感度为 88.9% (分界值为 30 0U/L) ,特异性为 87.2 % ;尿Amy的敏感性为 88.9% (分界值为 2 0 0 0U/L) ,特异性为84.6 % ;Uamy/Ucr的敏感性为 94.4% (分界值为 12 0U /mmolCr) ,特异性为 89.7% ;尿胰蛋白酶原 2试纸条法的敏感性为 94.4% ,特异性为 92 .3% ;B超检查的敏感性为 88.9%。结论 对急性胰腺炎的诊断 ,Uamy/Ucr比值比尿Amy的敏感性和特异性高 ,尿胰蛋白酶原
Objective To investigate the significance of urinary trypsinogen 2 dipstick test and the ratio of urinary amylase to urinary creatinine for the diagnosis of acute pancreatitis(AP). Methods A total of 57 consecutive patients who were suspected as AP presenting with abdominal pain at the emergency department experienced the test of serum and urinary amylase, urinary creatinine assay, urinary trypsinogen 2 dipstick and ultrasonography. Results There were 18 patients diagnosed as acute pancreatitis, the serum amylase assay had a sensitivity of 88.9 percent (cutoff value, 300 U per liter) and a specificity of 87.2 percent, the sensitivity and specificity of the urinary amylase assay and the ratio of urinary amylase to urinary creatinine were 88.9 (cutoff value, 2 000 U per liter), 94.4 (cutoff value, 120 U per mmol Cr), 84.6 and 89.7 percent, respectively. The sensitivity and specificity of the urinary trypsinogen 2 test strip were 94.4 and 92.3 percent. The sensitivity of the ultrasonography were 88.9 percent. Conclusion Urinary trypsinogen 2 dipstick test is a good index for the diagnosis of AP. The ratio of urinary amylase to urinary creatinine is also a useful index and may be better than urinary amylase for the diagnosis of AP.
出处
《中国普外基础与临床杂志》
CAS
2002年第1期38-39,共2页
Chinese Journal of Bases and Clinics In General Surgery
