摘要
目的探讨HBsAg ,CEA与结直肠癌肝转移的关系。方法 :回顾性分析二院 1990～ 1995年间收治的 5 82例结直肠癌病例 ,对术前HBsAg和CEA进行过测定 ,分别观察它们与肝转移之间的关系。结果 :发现HB sAg、(+)结直肠癌病例的肝转移明显低于HBsAg(- )病例 (P <0 .0 5 ) ;CEA(+)结直肠癌病例与CEA(- )病例的肝转移率之间无明显差别 (P >0 .0 5 ) ,但CEA(+)病例的 5年生存率 31%明显低于CEA(- )病例的84 % (P <0 .0 1)。结论 :结直肠癌较少转移至感染乙肝的肝脏 ,CEA不能作为判断肝转移倾向的指标 ,可以作为判断结直肠癌预后的指标之一。
Objective:To investigate the relation between HbsAg or CEA and liver metastases of colorectal cancer.Methods:The 582 patients with colorectal carcinoma were analysed retrospectively.Their HbsAg and CEA were assayed before operation.Results:The rate of liver metastases of colorectal cacer was significantly lower in the patients with HbsAg(+) than in the patients with HbsAg(-) ( P <0.05).It was not different in the patients with CEA (+),compared with those with CEA (-) ( P >0.05).While 5-year survival rate of patients with CEA(+) was significantly lower than that of patients with CEA(-) (31% via 84% P <0.01).Conclusions:Colorectal cancer which metastasizes to the liver is infected by HbsAg rarely;CEA is not a marker that is used to evaluate tendency of liver metastases for colorectal cancer,but it might be one of many markers that are used to evaluate the prognosis of colorectal cancer.
出处
《中国现代医学杂志》
CAS
CSCD
2002年第3期29-30,34,共3页
China Journal of Modern Medicine
