摘要
目的 探讨内窥镜逆行胰胆管造影 (ERCP)术后发生高淀粉酶血症的相关因素。方法 对 1999年 8月～ 1999年12月间长海医院行ERCP诊治的 2 72例病例资料进行回顾性分析。结果 (1)初学者操作发病率 6 7 2 %高于技术熟练者 40 %(P <0 0 1) ;(2 )诊断性ERCP组中胰管显影者发病率 5 1 9%明显高于胰管未显影者 2 6 3% (P <0 0 1) ,治疗性ERCP组中行乳头肌切开 (EPT)者发病率 6 8 1%高于放置支架者 46 7% (P <0 0 5 )和行鼻胆 (胰 )管引流者 12 5 % (P <0 0 1) ;(3)Oddi括约肌功能紊乱和胰腺疾病两组发病率分别为 78 6 %和 76 5 % ,明显高于其他疾病各组 (P <0 0 1) ,合并胆囊疾病组发病率为5 4 5 % ,明显高于单纯胆总管结石组 2 5 %和胰胆管显影正常组 2 1 1% (P<0 0 5 )。结论 ERCP术后发生高淀粉酶血症 ,主要与内镜医师操作技术的熟练程度、胰管显影、乳头肌切开和原发疾病等因素有关 ,而与患者性别、年龄及胆总管直径等因素无关。
Objective To evaluate the related factors of hyperamylasemia following endoscopic retrograde cholangiopancreatography. Methods By retrospective study(1999.8-1999.12),we analysed the clinical data of 272 patients following ERCP.Results (1)The incidence of hyperamylasemia following ERCP in beginner group was significantly higher than that in skilled group(P<0.01);(2)The incidence of pancreatic duct showing was 51.9%,significantly higher than that of bile duct showing only 26.3% (P<0.01)in diagnostic ERCP group,the incidence arising from papillosphincterotomy of the therapeutic ERCP group was 68.11%,significantly higher than that of putting stent 46.7% (P<0.05)and endoscopic nasal bile(or pancreatic) duct drainage(ENBD or ENPD)12.5% (P<0.01);(3)The incidence arising from dysfunction of the sphincter of Oddi group and the pancreatic disease group were 78.6%and 76.5% respectively,remarkably higher than that other groups(P<0.01);For diseased gall bladder group,the incidence were 54.5%,significantly higher than that in common bile duct stone group 25% (P<0.05) and the normal pancreaticobilliary duct showing group 21.1% (P<0.05).Conclusions The hyperamylasemia following ERCP was related primarily to the skill of endoscopist,pancreatic duct showing,papillosphincterotomy and preexisting disease state,but having nothing to do with age,sex and the diameter of the common bile duct.
出处
《武警医学》
CAS
2002年第1期11-13,共3页
Medical Journal of the Chinese People's Armed Police Force
关键词
经内窥镜逆行胰胆管造影
高淀粉酶血症
相关因素
Endoscopic retrograde cholangiopancreatography Hyperamylasemia Related factor
