摘要
目的 利用核素骨显像与CT导引下骶髂关节穿刺的病理活检结果 ,探讨核素骨显像骶髂关节与骶骨核素比值测定在强直性脊柱炎 (AS)诊断和监测中的价值 .方法 10例临床诊断AS的患者 ,共 19个骶髂关节 (正常关节1个 ,CT诊断为 0、Ⅱ、Ⅲ、Ⅳ期骶髂关节炎 18个 ) .先行核素全身骨显像、骶髂关节显像及其核素比值测定 ,1～ 3日后均行CT导引下骶髂关节穿刺活检 ,病理组织学检查 .结果 病理活检显示 18个为骶髂关节炎关节分别有滑膜炎、软骨及软骨下骨板血管翳侵入、骨质破坏等病变 .核素骶髂关节显像发现核素比值升高者 15个 .10例患者均有全身其他关节或脊柱病变 .结论 核素骨显像及其核素比值测定 ,有利于AS的骶髂关节炎的早期诊断 。
Objective To evaluate the value of early diagnosis and monitor the activity of ankylosing spondylitis(AS) by using scintigraphic imaging and histopathologic examination technology. Methods 10 patients with AS and 19 sacroliac joint of them were involvement,which divided into 4 groups:0 period;Ⅰ period;Ⅱ period;Ⅲperiod;Ⅳperiod according to modification of the New York criteria of AS.SPECT was performed on whole body skeleton as well as sacroiliac joint to measure the radioactivity ratio of it.After 1 to 3 days,they were performed CT guided centesis of sacroiliac joint for histopathologic exam. Results Histopathologic evidence showed synositis,enthesitis,intraarticular fibrous strands,new bone formation,and bony ankylosis in 18 sacroiliitis of AS.The ratio of sacroiliac joint/sacrum increased was 15 sacroiliac joint,and 10 AS patients were found abonrmality in other joint. Conclusions Bone scintigrphic imaging is not only to help to diagnose the AS in earlier stage,but also to monitor the activity of AS.
出处
《现代临床医学生物工程学杂志》
CAS
2001年第6期410-412,共3页
Journal of Modern Clinical Medical Bioengineering
关键词
强直性脊柱炎
骶髂关节
骨显像
组织病理学
CT导引
穿刺
Ankylosing spondylitis
Sacroiliac joint
Bone scintigraphic imaging
Histopathology
CT guided centesis
