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硝酸酯类药物的耐药及对策 被引量:4

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作者 李荣 李永金
出处 《临床荟萃》 CAS 北大核心 2002年第3期172-174,共3页 Clinical Focus
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参考文献15

  • 1Amsterdam E.Rational forintermittent nitrate therapy[J].Am J Cardiol,1992,70(1):57G.
  • 2Frishman WH,王景学,宋书凯.硝酸酯类药物治疗的耐药性、反跳现象和零时效应[J].国外医学(心血管疾病分册),1993,20(5):280-281. 被引量:3
  • 3Demots H.Glasser SP on behalf of the Transdermal Nitro Trial Study Group.Intermittlnt transdermal NTG therapy in the treatment of chronic stable angina[J].J Am CollCardiol,1989,13(4):786.
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  • 6杨浩,陈兵阳.硝酸甘油的耐药性是怎样形成的?[J].心血管病学进展,1995,16(5):309-311. 被引量:6
  • 7Lgnarro L.Edwards J,Gruetter D Y,et al.Possible in volvement of S-nitrosothiols inthe activation of guanylate cyclase by nitrous compounds[J].FEBS Lett,1980,110(2):275.
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  • 9Munzel T,Sayegh H,Freeman B A,et al.Evidence for enhanced vascular superoxideanion production in nitrate tolerance.A novel mechanism underlying tolerance andcross-tolerance[J].J Clin Invest,1995,95(1):187.
  • 10李昭晖.硝酸酯耐药的影响因素及对策[J].心血管病学进展,2000,21(2):95-97. 被引量:7

二级参考文献24

  • 1[1]Crandall L,Leake C,Loevenhart A,et al.A required tolerance to and cross-tolerance between the nitrous and nitricaid esters and sodium nitrite in man[J].J Pharmacol Exp Ther,1931,41:103
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  • 6[6]Boesgaard S,Aldershrile J,Enghusen H,et al.Nitrate tolerance in vivo is not associated with depletion of arterial or venous thiol levels[J].Circ Res,1994,74:115-120
  • 7[7]Münzel T,Mülsh A,Holtz J,et al.Mechanism of interaction between the sulfhydryl precursor L-methionion and glyceryltrinitrate[J].Circulation,1992,86:995-1003
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  • 9[9]Münzel T,Heitzer T,Kurz S,et al.Dissociation of coronary vascular tolerance and neurohomonal adjustment during long-term nitroglycerin therapy in patients with stable coronary artery disease[J].J Am Coll Cardiol,1996,27:297-303
  • 10[10]Rajagopalan S,Kurz S,Münzel T,et al.Angiotensin Ⅱ-mediated hypertension via membrane NADH/NADHP oxidase activation:contribution to alteration of vasomotor tone[J].J Clin Invest,1996,97:1916-1923

共引文献32

同被引文献28

  • 1姬晓鹏,蒋斌,黄河,潘琳.静滴单硝酸异山梨酯治疗充血性心衰25例疗效分析[J].中国社区医师(医学专业),2006,8(1):27-27. 被引量:1
  • 2孟繁波,隋凤花,陈兆杰,王克华,孙平辉,杨萍,王文志.硝酸异山梨酯直接静脉泵入治疗冠心病和高血压疗效分析[J].中国老年学杂志,2006,26(3):305-307. 被引量:7
  • 3喜杨,孙宁玲.硝酸酯类药物耐药的研究进展[J].中国临床药理学杂志,2007,23(3):213-216. 被引量:4
  • 4李金英,许恒忠.硝酸酯类药物的合理应用[J].中国药师,2007,10(7):709-711. 被引量:5
  • 5Panesar NS. Is steroid deficiency the cause of tolerance in nitrate therapy? Med Hypotheses,2000,55:310-313.
  • 6Abrams J, Elkayam U,Thadami U, et al. Tolerance : A historical overview. Am J Cardiol, 1998,81:3A-14A.
  • 7Gerzauich V, Ivanov A, Ivanova S, et al. Alternative splicing of cGMP-dependent protein kinase 1 in angiotensin-hypertension: nove 1 mechanism for nitrate tolerance in vascular smooth muscle. Circ Res,2003,93:805-812.
  • 8Munzel T, Giaid A, Kurz S, et al. Evidence for a role of endothelin and protein kinase C in nitroglycerin tolerance. Proc Natl Acad Sci USA, 1995,92:5244-5248.
  • 9Munzel T, Daiber A, Mulsch A. Explaining the phenomenon of nitrate tolerance. Circ Res, 2005,97:618-628.
  • 10Sydow K, Daiber A, Oelze M, et al. Central role of mitochondrial aldehyde dehydr ogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance. J Clin Invest, 2004,113 : 482- 489.

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