摘要
目的 探讨剖宫产手术对机体细胞免疫与体液免疫的影响。方法 对 6 7例接受剖宫产者的外周血T淋巴细胞亚群 (CD3、CD4 、CD8、CD4 /CD8比值 )及IgG、IgA、C -反应蛋白 (CRP)含量于术前、术后第 1天及术后第 7天分别进行了测定。结果 剖宫产组手术后第 1天外周血CD4 细胞减少 ,CD8细胞增多 ,CD4 /CD8比值降低 ,血IgG、IgA水平明显降低 ,而CRP含量升高 ,与手术前及对照组相比较 ,差异具有显著性 (P <0 0 5 ) ;但与术后第 7天相比 ,无显著性差异 (P >0 0 5 )。结论 剖宫产手术后机体出现短暂的细胞免疫与体液免疫功能降低 。
Objective To evaluate the effect of cesarean section on the cellular and humoral components of immune system.Methods T-lymphocyte subsets(CD 3,CD 4,CD 8,CD 4/CD 8 ratio),IgG,IgA and C-reaction protein(CRP)in peripheral blood of pregnant women were measured before and after cesarean section of 1 and 7 days respectively in operation group,and also detected in control group.Results First day after cesarean section,the peripheral blood detection showed reduced content of CD 4 lymphocytes,CD 4/CD 8 ratio,IgG and IgA,and a marked increase of the content of C-reaction protein and CD 8 lymphocytes,all of them showed significant difference compared with pre-operation and normal control(P<0\^05).No difference by day 7 after operation(P>0\^05).Conclusion There is transient cellular and humoral immunologic depression after cesarean section.These changes are most likely to be caused by the surgical intervention and anesthesia.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2001年第11期669-670,共2页
Chinese Journal of Practical Gynecology and Obstetrics
