摘要
目的 :探讨金水六君煎口服液对慢性支气管炎小鼠血清超氧化物歧化酶 (SOD)活力及丙二醛 (MDA)含量的影响。方法 :采用烟熏方法复制慢性支气管炎模型小鼠 ,并用金水六君煎口服液治疗 ,检测小鼠血清SOD活力与MDA含量。结果 :金水六君煎口服液高剂量组SOD活力〔(0 67± 0 15 )NU/L〕增高 ,与模型组〔(0 39± 0 13)NU/L〕比较 ,差异有显著性 (P <0 0 1) ;MDA含量〔(9 2 6± 2 90 )nmol/L〕降低 ,与模型组〔(16 0 7± 5 62 )nmol/L〕比较 ,差异有显著性 (P <0 0 1)。结论
Objective: To study the effect of Jinshui Liujun Jian Oral Liquid (JLJOL) on serum superoxide dismutase (SOD) activity and malonyldialdehyde (MDA) content in mice with chronic bronchitis.Methods: JLJOL was given to the chronic bronchitis mice model (induced by smoking) through gastrogavage, and then SOD activity and MDA content were tested. Results: SOD activity in model mice after JLJOL treatment was 0 67±0 15 NU/L, which was significantly higher than that in the untreated model (0 39±0 13 NU/L, P<0 01). But the MDA content in treated mice was significantly lower than that in untreated one (9 26±2 90 nmol/L vs 16 07±5 62 nmol/L, P<0 01). Conclusion: JLJOL could scavenge the injury of free radical on organism.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2001年第11期843-844,共2页
Chinese Journal of Integrated Traditional and Western Medicine
基金
国务院侨办立项 (No.93 - 98- 6)
关键词
金水六君煎
慢性支气管炎
血清超氧化物歧化酶
丙二醛
Jinshui Liujun Jian Oral Liquid, chronic bronchitis, pathological model, serum superoxidase dismutase, malonyldialdehyde
