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自身免疫性多腺体综合征的研究进展 被引量:6

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摘要 自身免疫性多腺体综合征 (APS)与体液免疫和细胞免疫有关 ,体液免疫中的多个器官特异性抗体如谷氨酸脱羧酶抗体、5 5KD蛋白抗体等和细胞免疫中的多个细胞因子如白介素 1β、γ 干扰素等参与了APS的发病机制 ,导致内分泌腺体功能减退或亢进。APSI好发于儿童 ,基因突变在自身免疫调节因子AIRE上 ,APSⅡ好发于女性 ,与人类白细胞抗原 (HLA)
出处 《国外医学(内分泌学分册)》 2001年第6期325-327,共3页 Foreign Medical Sciences(Section of Endocrinology)
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参考文献15

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同被引文献24

  • 1刘晓平.糖尿病从五脏辨治[J].中医药学刊,2005,23(10):1906-1907. 被引量:3
  • 2王玉,林汉华.自身免疫性多腺体综合征的诊断和治疗[J].实用儿科临床杂志,2006,21(8):457-459. 被引量:15
  • 3吴迪,朱逞,巩纯秀,桑艳梅.自身免疫多腺体综合征、1型糖尿病、自身免疫甲状腺病与白细胞抗原-Ⅱ类基因研究进展[J].实用儿科临床杂志,2006,21(20):1426-1428. 被引量:6
  • 4国外医学内分泌学分册编辑部.IA-2抗体与日本1型糖尿病者的HLA表型及自身免疫性甲状腺疾病有关[J].国外医学:内分泌学分册,2001,21(6):332-332.
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