摘要
【目的】调查非肝病人群中经输血传播病毒 (TTV)的感染状况。【方法】在TTVORF1保守区设计引物 ,用巢式PCR检测 12 5例医院工作人员、10 5例献血员、46例静脉透析病人、16 6例性病高危人群和 83例静脉药瘾者 ,共 5 2 5人血清中TTVDNA。【结果】TTVDNA阳性率 ,医院工作人员 3 2 %、献血员 11 4%、静脉透析病人 13 0 %、性病高危人群 2 0 5 %和静脉药瘾者 39 8%。【结论】静脉药瘾者、性病高危人群和静脉透析病人是TTV感染的高危人群。
To investigate the infection of transfusion transmitted virus(TTV) in the people without liver diseases. A nested polymerase chain reaction(PCR) assay was established to detect TTV DNA in the serum samples of 125 the persons working in hospitals, 105 blood donors, 46 patients with hemodialysis,166 sexually transmitted diseases(STD) high risk population and 83 intravenous drug users(IVDU). The results showed that the positive rate for TTV DNA in the serum samples of the persons working in hospitals, blood donors, patients with hemodialysis, STD high risk population and IVDUs were 3 2%?11 4%?13 0%?20 5%and 39 8 %respectively. [Conclusion] IVDUs, STD high risk population and the patients on hemodialysis were the high risk population for TTV infection.
出处
《中山医科大学学报》
CSCD
北大核心
2001年第6期463-465,共3页
Academic Journal of Sun Yat-sen University of Medical Sciences
基金
广东省自然科学基金资助项目 ( 940 2 31)
中山医科大学科研启动基金资助项目 ( 98A110 )
