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209例眼眶特发性炎性假瘤的临床分析 被引量:8

A clinical analysis of 209 cases of idiopathic orbital inflammatory pseudotumor
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摘要 目的 :探讨眼眶特发性炎性假瘤的临床特点和治疗效果。方法 :回顾分析我中心自 1978年 1月到 1999年 12月收集的眼眶特发性炎性假瘤 2 0 9例。结果 :2 0 9例中 ,男 118例 ,女 91例 ;就诊年龄 4~ 80岁 (平均 44 4岁 ) ;右眼 90例 ,左眼 81例 ,双眼 38例。眼球突出( 6 6 % )、眶缘可触及肿物 ( 6 5 % )、眼睑肿胀 ( 5 5 % )、眶压增高 ( 5 5 % )和眼球运动受限 ( 4 8% )为最常见的表现。根据影像学和手术所见 ,以眼眶内占位性病变表现者最多见 ( 4 3% ) ,其次为泪腺炎型 ( 32 % )、弥漫型 ( 10 % )和肌炎型 ( 8% )。视神经周围炎型 ( 2 % )、巩膜周围炎型 ( 2 % )、急性型 ( 2 % )与眼睑型 ( 1% )少见。经手术、全身用激素或免疫抑制剂和眼眶局部放射治疗后随访结果 (平均随访 1 5年 )显示完全治愈率和部分治愈率分别为 40 %和 5 7% ,其中随访半年以上的 80例病人中有 43%复发。结论 :尽管眼眶特发性炎性假瘤容易复发 ,但手术切除。 Objective:To observe the clinical findings and response to treatment in patients idiopathic orbital inflammatory pseudotumor. Methods:209 idiopathic orbital inflammatory pseudotumor cases were evaluated retrospectively. Results:Of the 209 cases,118 were male and 91 were female;there were 90 in the right eye,81 left eye and 38 both eyes.Patient′s age ranged from 4 to 80 years(mean 44 4).Proptosis(66%),palpable mass(65%),swollen eyelid(55%),increased orbital pressure(55%)and motility restriction(48%)were the five most common signs.According to radiological and surgical findings,focal mass within orbit was the most frequent subtype(43%),followed by lacrimal inflammatory pseudotumor(32%),diffuse orbital inflammation(10%)and myositis(8%).Perineuritis(2%),periscleritis(2%),acute inflammation(2%)and eyelid pseudotumor(1%)were rare clinical findings.The response to treatment(with a mean follow up of 1 5 years)showed that the cure rate was 40% and the effective rate 97% after combined management of surgical resection,systemic steroid and local low dose radiotherapy. Conclusions:Although recurrence of IOPT is common,the success rate of treatment for this group of patients is high.
出处 《中国实用眼科杂志》 CSCD 北大核心 2002年第1期43-46,共4页 Chinese Journal of Practical Ophthalmology
关键词 炎性假瘤 眼眶 治疗 Pseudotumor,Orbit,Treatment
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