摘要
目的 :研究颅内动脉瘤破裂出血后低钠血症发生率及其与 Fisher分级和脑血管痉挛的关系。 方法 :1998年 3月至2 0 0 1年 5月采用可脱性弹簧圈 (GDCs)栓塞治疗颅内破裂动脉瘤 15 0例 ,按解剖部位分成前交通 (ACo A )、后交通 (PCo A )和大脑中动脉 (MCA )动脉瘤 3组 ,分析低钠血症发生率。 结果 :3组低钠血症发生率分别为 48%(32 / 6 7)、15 %(8/ 5 2 )和 16 %(5 / 31) ,重度低钠血症发生率分别为 30 %(2 0 / 6 7)、6 %(3/ 5 2 )和 6 %(2 / 31)。 ACo A组中 ,Fisher分级 ～ 级和 ～ 级低钠血症的发生率分别为 6 7%(2 0 / 30 )和 32 %(12 / 37) ;有脑血管痉挛和无脑血管痉挛患者中低钠血症的发生率分别为 71%(2 4/ 34 )和 2 4%(8/ 33)。结论 :ACo A组低钠血症与重度低钠血症发生率明显高于 PCo A组和 MCA组 ,ACo A动脉瘤破裂出血 Fisher分级 ～ 级或并发脑血管痉挛患者低钠血症发生率高。
Objective: To investigate the hyponatremia incidence in patients with ruptured intracranial aneurysms and the correlation with Fisher grading and cerebral vasospasm. Methods: Totally 150 patients with ruptured intracranial aneurysms from March 1998 to May 2001 were divided into anterior communicating artery (ACoA) group,posterior communicating artery (PCoA) group and middle carotid artery(MCA) group according to the sites of aneurysms.The patients were treated with GDCs interventionally and the incidences of hyponatremia were analyzed. Results: The incidences of hyponatremia in 3 groups were 48%(32/67),15%(8/52) and 16%(5/31),respectively; The incidences of severe hyponatremia of 3 groups were 30%(20/67),6%(3/52) and 6%(2/31), respectively. In ACoA group, the incidences of hyponatremia in Fisher grade Ⅲ-Ⅳ and Ⅰ-Ⅱ were 67%(20/30) and 32%(12/37) and the incidences with and without vasospasm were 71%(24/34) and 24%(8/33), respectively. Conclusion: The ACoA group has a significantly higher incidence of common and severe hyponatremia than the other groups. In ACoA group,hyponatremia is significantly more often in Fisher grade Ⅲ-Ⅳ cases and those with vasospasm.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2002年第1期79-80,共2页
Academic Journal of Second Military Medical University
基金
国家自然科学基金资助项目 ( C0 30 30 30 7)
