摘要
目的:观察不同浓度的虎茵汤对D-GalN(D-半乳糖胺)致急性肝损伤的保护作用。方法:采用化学毒性物质D-GalN致小鼠急性肝损伤为模型,测定高低剂量的虎茵汤对肝损伤ALT、AST及肝组织病理改变。结果:高剂量组虎茵汤同联苯双酯一样能够明显降低D-GalN致小鼠肝损伤血清ALT、AST值升高(P<0.01),减轻对肝脏细胞的病理损伤,说明虎菌汤对急性肝损伤具有明显保护作用。
Objective: The model of liver injury caused by D-GalN was used. Methods: We observed the protective effect of the Huyintang of different doses on experimental liver injury and histopathological changes. Results: The Huyintang like Lianbenshuangzhi, markedly decreased ALT and AST increase caused by liver injury by D-GalN. Conclusion: Huyintang has an obvious protection effect on experimental liver injury in mice.
出处
《黑龙江医药科学》
2001年第6期15-16,共2页
Heilongjiang Medicine and Pharmacy
