摘要
目的:探讨胶质瘤发生发展的危险因素。方法:通过档案及旁证法等确定脑胶质瘤129例作研究组,另选条件相似的同期入院的非神经系统疾病的住院患者258例作为对照组。采用配比对照研究方法,分别进行采集、调查、登记表格,逐一统计分析应急事件、不良嗜好、接触化学性和物理性及患者是否食用新鲜蔬菜水果等,经统计学处理,揭示年龄、性别、先天遗传、物理化学生物等因素对胶质瘤的影响。结果:研究组与对照组的不良生活习惯(吸烟、饮酒、嗜食咸鱼、不喜欢新鲜蔬菜、水果)、性格与心理状态、应急事件、接触汽油、柴油、农药者均有显著性差异(P<0.01);研究组与对照组的性别与年龄、头部外伤及接触放射线、电磁辐射无显著性差异(P>0.05)。结论:患者存在一定内因(脑细胞中的原癌基因、性格内向、心理状态不稳定)的基础上,在外因(不良嗜好、化学性和物理性毒性污染)作用下,细胞中的原癌基因被活化,从而形成真正的肿瘤实体。
Objective: To discuss risk factors of occurrence and development. Methods: To use 129 cases of glioma as the investigation group and to select 258 cases of other deseases as control group.To investigate factors including age,sex,heredity,physics, chemistry, Stress, living hadit, character, physiological condition, etc. in human glioma. Result: There were significantdifference in living habit, character physiological condition, stress, exposure to gasoline and pesticide in both groups (P<0.01). There was no difference in sex ,head injury and exposure to radiation and electromagetism in both groups (P>0.05). Conclusion: The cancer gene is activated due to internal and external cause, leading to glioma occurrence.
出处
《黑龙江医药科学》
2001年第6期11-12,共2页
Heilongjiang Medicine and Pharmacy
