摘要
目的 为寻找更安全、有效和简便的维生素 E给药途径治疗新生儿硬肿症。方法 将 6 8例新生儿硬肿症患者随机分为维生素 E小剂量肌内注射组 (对照组 38例 )和大剂量经皮给药组 (治疗组 30例 )。并观察其硬肿消退时间、住院时间、有效率、死亡率等指标。结果 治疗组比对照组在硬肿消退时间、住院时间显著缩短 (P<0 .0 0 1) ,有效率增高 (P<0 .0 0 1)死亡率下降 (P<0 .0 0 1)。结论 应用大剂量维生素 E经皮吸收治疗新生儿硬肿症优于常规小剂量肌内注射法 ,是一种高效、安全和简便的方法 ,值得临床推广。
Objective To explore a secure, effective and convenient method to use vitamin E to treat scleredema neonatorum. Methods [WT6BZ]68 patients with scleredema neonatorum were randomly divided into two groups: the control and the experimental. In control, 38 cases were administrated with small-dosage vitamin E through muscular injection, while in experimental, the rest 30 cases with large-dosage vitamin E by way of dermal absorption. Such indexes as extinction time of scleredema neonatorum, duration of staying in hospital, healing rate and death rate were observed. Results Compared with control, the extinction time of scleredema neonatorum and duration of staying at hospital in the experimental group were shortened significantly (P<0.001), and both healing and mortality rates were significantly higher (P<0.001). Conclusion Vitamin E at large-dosage to treat scleredema neonatorum via skin absorption is more effective than through small dosage muscular injection. It is a secure, effective and convenient therapy in treating scleredema neonatorum.
出处
《南方护理学报》
2001年第3期37-38,共2页
Nanfang Journal of Nursing
关键词
新生儿硬肿症
维生素E
护理
scleredema neonatorum
vitamin E
nursing care
