摘要
目的 :研究低分子肝素 (L MWH)防治血液透析 (HD)中急、慢性肾功能衰竭患者的出血倾向。方法 :对 2 8例肾衰伴急性出血患者选用速避凝做抗凝剂 ,在每次血透前注入速避凝 0 .4ml共做 HD 15 0次 ,均顺利完成透析全过程。结果 :无透析器及管路凝血 ,未发现原有出血加重或发生新的出血灶 ,穿刺压迫止血时间平均 5 .12± 1.1分钟。结论 :L MWH能有效阻止血液在体外循环中凝固 。
OBJECTIVE:To study the application of low molecular weight heparin (LMWH) in acute and chronic renal failure patients to avoid hemorrhagic tendency during hemo dialysis (HD). METHODS:28 patients with acute bleeding tendency received 0.4ml an of anticoagulation Fraxiparine intravenous injection before per HD. All subjects had 150 HD and finished the process successfully. RESULTS:There wasn't any blood coagulation in the dialysis machine and within vessel. New sites or further aggravation of the bleeding aren't found, the pressure time is 5.0±1.0 minutes at the puncture sites in LMWH. CONCLUSTIONS:LMWH can prevent clot formation from extracorporeal circulation effectively without bleeding complication.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2001年第4期326-327,共2页
Chinese Journal of Modern Applied Pharmacy
关键词
低分子肝素
血液透析
出血倾向
肾功能衰竭
Low molecular weight heparin
Bleeding
Renal failure
hemodialysis
