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慢性阻塞性肺疾病肺动脉高压的无创伤性诊断

Diagnosis of Pulmonary Artery Hypertension in Chronic Obstructive Pulmonary Diseases by Pulmonary Perfusion Tomographic Imaging
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摘要 目的 :探讨肺灌注断层显像检测慢性阻塞性肺疾病 (chronicobstructivepulmonarydiseases ,COPD)肺动脉压力的应用价值。方法 :对 30例COPD病人及 10例健康人进行肺灌注平面、断层显像。分别求得断层及平面肺上、下 1/3平均放射性计数的比值。结果 :病例组平面显像方法计数比为 1.0 2± 0 .2 8,断层显像方法计数比为 1.2 1± 0 .18,两法之间差异显著 (P <0 .0 5 ) ;对照组断层显像计数比为 0 .89± 0 .0 3,与病例组断层显像相比 ,差异极显著 (P <0 .0 1) ;而对照组平面显像方法计数比为 0 .87± 0 .0 5 ,与其断层显像方法计数比 ,差异不显著 (P>0 .0 5 )。结论 Objective: Our aim was to find a diagnostic method for pulmonary arterial hypertension(PAH) in patients with chronic obstructive pulmonary diseases (COPD) by pulmonary perfusion tomography. Methods: Ten healthy subjects and 30 patients with COPD underwent pulmonary perfusion tomography with technetium 99m labelled macroaggregated albumin( 99m Tc MAA) . The ratio of the average counts in the upper third region to the average counts in the lower third region(U∶L zone ratio) was caculated for posterior planar image and coronal tomogram image. Results: In the patients group, the U∶L zone ratio of tomography method was 1.21±0.18, and the U∶L zone ratio of planar imaging method was 1.02±0.28 . The difference between these two methods was significant (P<0.05).When the tomography method was employed, the U∶L zone ratio of healthy group was 0.89±0.03,the difference between the two groups was significant (P<0.01). In the healthy subjects, the U∶L zone ratio was 0.87±0.05. No significant difference existed between the U∶L zone ratio of tomography method and that of planar method (P>0.05). Conclusion: Comparing with planar imaging, the pulmonary perfusion tomography seems to be more accurate in diagnosing pulmonary hypertension in patients with COPD.
作者 张驰 张彩霞
出处 《中国医科大学学报》 CAS CSCD 北大核心 2001年第5期378-380,共3页 Journal of China Medical University
关键词 肺疾病 体层摄影 慢性阻塞性肺疾病 诊断 肺动脉高压 pulmonary disease, obstructive hypertension,pulmonary tomography emission computed single photon
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