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重型颅脑损伤早期肠内营养支持的临床研究 被引量:8

Clinical study of early enteral feeding in severe head injury
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摘要 目的 探讨颅脑损伤后早期肠内营养支持疗法的特点。方法 将 40例经临床或CT证实为重型颅脑损伤病例随机分成两组 ,分别早期给予肠内营养 (earlyenteralfeeding,EEF)与肠外营养 (totalparenteralnutrition ,TPN) ,在摄入同等热量、同等氮量的条件下 ,对两组有关临床数据进行比较。结果 EEF组 2 4小时排氮量明显少于TPN组 ,氮平衡、肌酐身高指数 (ICr)等营养指标优于TPN组。伤后 2 8天 ,EEF组体重丢失显著少于TPN组 ,GCS评分较TPN组显著改善。结论 EEF可维持胃肠道粘膜结构的完整性 ,促进消化吸收功能的恢复 ,减轻伤后分解代谢 。 Objective To discuss the advantage of early enteral feeding in severe head injury.?Methods Forty cases were divided randomly into two groups,early enteral feeding group(EEF) and total parenteral nutrition group(TPN),each of which equal quantity of heat and nitrogen had been given.?Results Twenty forty hours quantity of nitrogen excreted was less obviously in the EEF than that in the TPN.EEF is superior to TPN in nitrogen balance,index of creatinine and stature(ICr),etc.Twenty eight days after injury,weight loss of the EEF was less apparently than that of the TPN group.GCS were better in EEF than that in the TPN.?Conclusion EEF can maintain integrality of gastrointestinal mucosa,help to recover digestive and absorptive function,moderate post traumatic catabolism,and improve nourishment and consciousness.
出处 《创伤外科杂志》 2002年第1期24-25,共2页 Journal of Traumatic Surgery
关键词 颅脑损伤 肠内营养 肠外营养 head injury enteral nutrition parenteral nutrition
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参考文献4

  • 1[1]Robbert PR.Nutrition in the head-injuried patient[J].New Horiz,1995,24(3):506-517.
  • 2[2]Jonathan M,Saxe MD,Anna M.Lower esophageal sphincrer dysfunction precludes safe gastric feeding after injury[J].J Trauma,1994,37(4):581-586.
  • 3[3]Weekes E,Elia M.Observation on the patterns of 24-hour energy expenditure changes in baby composition and gastric emptying in head injured patients receiving nasogastric tube feeding[J].J Parenter Enter Nutr,1996,20(1):31-37.
  • 4[4]De Deyne C,De Jongh R,Mercks L,et al.Early enteral feeding in cranial trauma[J].Ann Fr Anesth Reanim,1998,17(2):192-194.

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