摘要
利用高效液相色谱从商品化伊维菌素中分离出８种组分，再与ＥＳＩ－ＭＳ－ＭＳ偶合，得到其加合离子和特征子离子，从而对各组分的化学成分进行了鉴定。报道了伊维菌素Ｂｌａ的１３Ｃ ＮＭＲ谱图，并对碳信号作了归属。
8 fractions of commercial ivermectin were isolated and identified by high performance liquid chromatography-electrospray-mass spectrometry-mass spectrometry (HPLC-ESI-MS-MS). The molecular ions themselves were not seen in the ESI-MS spectra, but adduct ions such as [M + Na](+) ions were prominent. The MS-MS data of HPLC fractions were also obtained by the ESI-triple quadrapole mass spectrometer. The charaeteristic daughter ions could be used to distinguish the same molecular weight components. The C-13 nuclear magnetic resonance (NMR) spectrum of ivermectin B-1a was reported and explained with its structure.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
2002年第1期26-30,共5页
Chinese Journal of Analytical Chemistry
