摘要
目的 :了解吡柔比星 (THP)与丝裂霉素C(MMC)膀胱灌注预防膀胱肿瘤术后复发的疗效。方法 :将 5 0例膀胱肿瘤术后患者分为两组 ,分别接受THP、MMC治疗 ,随访 12～ 18个月。结果 :THP组 31例 ,复发 2例 ,复发率为 6 .5 % ;MMC组 19例 ,复发 8例 ,复发率 4 2 .1% ,两组相比差异有显著性意义 (P <0 .0 5 )。结论 :THP膀胱灌注预防膀胱肿瘤术后复发效果满意 。
Purpose:To investigate the effect of Pirarubicin or Mitomycin C by using intravesical treatment to prevent postoperative recurrence of bladder cancer.Methods:50 patients with bladder cancer after TURBt or partial cystectomy were divided into two groups to receive intravesical treatment with Pirarubicin or Mitomycin C respectively. All these patients were followed up for 12 to 18 month.Results:Recurrence rate in the patients treated with Pirarubicin was 6.5 %(2/31) and 42% (8/19) in the patients treated with Mitomycin C.Conclusions:The rate of recurrence in group treated with Pirarubicin was lower than that in Mitomycin C treated group. Pirarubincin may be more effective in the prevention of bladder cancer recurrence after TURBt or partial cystectomy.
出处
《临床泌尿外科杂志》
2001年第12期524-525,共2页
Journal of Clinical Urology
