摘要
重度甲亢组血浆心钠素浓度明显高于正常组,轻中度甲亢组、甲减组与正常组比较无显著差异,甲亢病人经治疗症状控制者较治疗前明显下降,症状未控制者较治疗前无明显改变,甲减病人治疗前后无明显改变。血浆cGMP浓度病人组与正常组比较及治疗前后皆无明显差异。未经治疗的甲亢病人心钠素与T_4、心率呈正相关,与cGMP无相关性。
Plasma ANP concentration in 20 patients with severe hyperthy-
roidism was significantly higher than that in normal subjects.No significant
difference in plasma ANP level was found in mild,moderate hyperthyroidism
and hypothyroidism as compared with normal subjects.Symptoms controlled
patients showed significant decrease in ANP level while no significant change
in ANP was noted in noncontrolled patients in hyperthyroidism.Change in
ANP level was insignificant between pre-and postadministrated in hypothy-
roidism.Plasma cGMP concentration in patients and preadministration group
showed no significant change as compared with normals and postadministra-
tion group respectively.Positive correlation between ANP and T_4,HR but
not cGMP was found in 53 pretreated patients.Thus,thyroid hormone
might be a regulating factors of circulation ANP level.
出处
《山东医科大学学报》
1991年第1期47-50,共4页
Acta Academiae Medicinae Shandong
关键词
心钠素
甲亢
甲减
乌苷环一磷酸
Atrial natriuretic peptide
Guanosine cyclic monophosphate
Hyperthyroidism
Hypothyroidism
