摘要
用抗S100蛋白抗血清对面部播散粟粒状狼疮、着色真菌病、疥疮、日光性皮炎、银屑病及扁平苔藓的病损行免疫组化染色。前4种病真皮淋巴细胞浸润灶中均可见较多的S100蛋白阳性细胞(+++、++++),而在浆细胞密集区阳性细胞则很少或没有。表明此种细胞与炎症发生有关,但无疾病特异性,与郎格罕氏细胞的抗原提呈作用相一致。
The sections taken from the cutaneous lesions ot lupus miliaris
disseminatus faciei(2 cases),chromomycosis(2 cases),scabies(3 cases),
solar dermatitis(5 cases),psoriasis vulgaris(4 cases),and lichen planus
(38 cases)were stained immunohistochemically using anti S100 protein anti-
serum.In the first four diseases,many S100 protein positive cells(+++,++++)
were found in the dermal dense inflammatory infiltrate,at least in some areas,
whereas less numerous cells in the epidermis in most cases.In the lesions of
lichen planus S100 protein positive cell varied in number from(+)to(++++).
There were few-positive cells in the lesion of psoriasis vulgaris.The dermal
positive cells lay in close approximation to the lymphocytes,but hardly occured
in the infiltrate consisting mainly of plasma cells.The distribution of the
S100 protein positive cells was in conformity with the capacity of Langerhans
cell to present antigen.Our observation suggests that these cells may play an
important role in the pathogenesis of inflammation in many diseases of diverse
etiology.
出处
《山东医科大学学报》
1991年第1期26-28,共3页
Acta Academiae Medicinae Shandong
