摘要
为了研究高脂血症痰瘀辨证的病理机制 ,在临床辨证的基础上 ,对 35例痰瘀阻络证、33例脾虚痰凝证及2 9例非痰非瘀证和 30例健康对照组进行了中医症征积分和血脂、血流动力学检测及相关分析。结果显示痰瘀阻络证和脾虚痰凝证病人的血脂和血流动力学显著异常于两对照组 ,“痰凝”症征积分与高密度脂蛋白 (HDL C)、低密度脂蛋白 (LDL C)呈高度相关 ,而“血瘀”症征积分与总胆固醇 (TC)及每搏输出量 (SV)、射血分数 (EF)、总外周阻力(RT)、血管弹性 (C)均高度相关 ,提示血脂升高是高脂血症“痰浊内阻”病理的物质基础 ,而高血脂并见心功能减低是其“由痰致瘀”
To study the pathological mechanism of differentiation of phlegm stasis in hyperlipemia,We examined and analyzed clinical manifestations in TCM syndromes,blood fat and hemodynamics in 35 cases of obstruction of vessels due to phlegm stasis (OVPS),33 cases of obstruction of vessels due to spleen insufficiency and phlegm accumulation(OVSP),29 cases of syndromes without phlegm and bloodstasis(SWPS) in hyperlidemia,and 30 normal adults(NA).The results showed that the data of blood fat and hemodynamics of the OVPS and OVSP were significantly abnornal,compared with SWPS and NA( P <0 05 or<0 01).Manifestations of phlegm accumulation were highly related to HDL C and LDL C,and those of blood stasis were highly related to TC,SV,EF,RT and C.The results indicate that increased blood fat is material base of accumulation of phlehm in hyperlidemia,and high blood fat level and low heart function are pathophysilogical features of blood stasis caused by phlegm in hyperlipemia.
出处
《湖南中医学院学报》
2001年第3期1-4,共4页
Journal of Hunan College of Traditional Chinese Medicine
基金
湖南教育委员会科研项目 ( 96 12 6 )
关键词
高脂血症
痰瘀辨证
血脂
血流动力学
hyperlipemia
differentiation of phlegm stasis
bloodfat
hemodynamics
