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血小板生成素临床研究 被引量:6

The Clinical study on Thrombopoietin
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摘要 血小板生成素(thrombopoietin,TPO)是近年来新发现的造血生长因子.目前科学家们不但对其基因定位、分子结构、生物学效应等方面进行了深入的研究,并且已成功地制备了两种重组人血小板生成素(recombinant human thrombopoietin,rhTPO).
出处 《医学研究通讯》 2001年第12期28-31,共4页 Bulletin of Medical Research
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  • 1张敬宇,杨琳,罗建民,董作仁.环孢菌素A联合小剂量泼尼松治疗难治性特发性血小板减少性紫癜[J].医师进修杂志,2004,27(9):32-33. 被引量:6
  • 2Ktete DJ,Begley CG.Recombinant human thrombopoietin:basic bilolgy and evaluation clinical studies[J].Blood,2002,100(10):3457.
  • 3Kosugi S, Kurata Y, Tomiyama Y, et al. Circulating thrombopoietin level in chronic immune thrombocytopenic purpura. Br J Haematol,1996, 93:704-706.
  • 4Usuki K, Tahara T, Iki S, et al. Serum thrombopoietin level in various hematological diseases. Stem Cells, 1996, 14:558-565.
  • 5yon dem Borne A, Folman C, van den Oudenrijn S, et al. The potential role of thrombopoietin in idiopathic thrombocytopenic purpura. Blood Rev, 2002, 16:57-59.
  • 6Shinjo K,Takeshita A,Nakamura S,et al.Serum thrombopoietin levels in patients correlate inversely with platelet counts during chemotherapy-induced thrombocytopenia[J].Leukemia,1998,12:295-300.
  • 7Saroj VR,Claire FV,Carlos BR,et al.Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic cancer[J].Ann Intern Med,2000; 132:364-368.
  • 8Wolff SN,Herzig R,Lynch J,et al.Recombinant human thrombopoietin (rhTPO) after autologous bone marrow transplantation:a phase I pharmacoknetic and phamacodynamic study[J].Bone Marrow Transplantat,2001 ;27:261-268.
  • 9张源慧.特发性血小板减少性紫癜[A].见:张之南 沈悌 主编.血液病诊断及疗效标准 第2版[C].北京:科学出版社,1998.279-285.
  • 10沈晓明,王卫平.儿科学[M].7版.北京:人民卫生出版社,2008:93.

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