摘要
本文报道了(三唑基-14C)-粉锈宁的制备。由14C-甲酸和重碳酸氨基胍形成(5-14C)-3-氨基-1,2,4-三唑,再经重氮化脱氨得到(5-14C)-1,2,4-三唑,最后再与对氯酚和二氯片呐酮反应得到(三唑基-14C)-粉锈宁。放化收率为26％(从甲酸-14C计),放化纯度大于95％。
The fungicide 1-(4-chloro-phenoxy-)3,3-dimethyl-1(1-H, 1,2, 4-triazollyl-) 2-butanone ( Triadimefon ) was labelled with 14C in triazole group. The synthesis was accomplished in three steps starting with 14C-formic acid and aminoguanidine bicarbonate, Formed(5-14C)-3-amino-1-H-1,2, 4-triazole was deaminated by diazotization and got(5-14C )-1, 2, 4-triazole It reacted with p-chlorophenol and 1, l-dichloro-3,3-dimethy1-2-butanone in acetone, and 14C-Triadimefon was synthesized. Radiochemical yield was 26%(based on 14C-formic acid) .Radiochemical purity was more than 95%.
出处
《核农学报》
CAS
CSCD
1989年第1期61-64,共4页
Journal of Nuclear Agricultural Sciences
