摘要
应用电镜分别对 5例不同类型白血病患者骨髓穿刺细胞进行了观察 ,观察结果表明例一、二均为急性早幼粒细胞白血病 ,两例骨髓细胞中均见有许多异常早幼粒细胞胞浆内含有Auer小体 ,但两例细胞内Auer小体结构呈明显差异。例三、四为不同类型毛细胞白血病 ,即典型毛细胞白血病 (Ⅰ型 )及变异型毛细胞白血病 (Ⅱ型 ) ,两型细胞在结构上的差异主要表现为细胞膜表面毛样突起的长度及数量不同。变异型毛细胞白血病细胞的特点仅在电镜下才能辨认。例五为急性粒细胞白血病的部分分化型 ,其中早幼粒细胞胞浆内仅具极少数小的电子致密颗粒 ,电镜对该种细胞的分辨显示出光镜所不具有的优势 。
Bone marrow aspiration specimens of 5 different leukemia patients were electron microscopically observed. The results showed that the both as acute premyelocyte leukemia diagnosed cases (case 1 and 2) revealed many abnormal premyelocytes which contained cytoplasmic Auer bodies with markedly different structures. The case 3 and 4 were diagnosed as different types of hairy cell leukemia, namely typical hairy cell leukemia (type Ⅰ) and atypical hairy cell leukemia (type Ⅱ). The morphological difference of both type Ⅰ,Ⅱ cells were expressed mainly in the different lengths and numbers of the hairy processes on the cell surface and these differences can only be observed electron microscopically. The case 5 was a partly differentiated type of acute myelocytic leukemia and the cytoplasm of the premyelocyte contained only a few electron dense granules. The electron microscopy of these cells showed a marked superiority in its resolving power than the light microscopy and suggested its significance also in the diagnosis of leukemia.
出处
《电子显微学报》
CAS
CSCD
北大核心
2001年第6期685-689,共5页
Journal of Chinese Electron Microscopy Society
关键词
白血病
电镜诊断
骨髓细胞
leukemia
electron microscopyic diagnosis
