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生长相关蛋白与神经发育、可塑性和再生的关系 被引量:5

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摘要 神经系统发育过程中,轴突的方向性生长是形成复杂而严密的神经网络所必需的要素.轴突之所以能沿适当的路径生长,正确识别靶细胞并与之建立突触联系,结构-生长锥发挥了重要的作用.生长中的轴芽尖端膨大,形成一个富含肌动蛋白的丝状伪足样结构,称为生长锥(growth cones).生长锥的丝状伪足端用来探测远侧环境,若接触到可以粘附的基质,丝状伪足的尖端则粘附在基质结构上并牵拉整个生长锥向远侧粘附部位移动.生长锥如何沿伸向一定的部位,曾有不同的学说.
出处 《中国局解手术学杂志》 2001年第3期312-315,共4页
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