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心肌肌钙蛋白Ⅰ对心肌损伤的诊断价值

Diagnostic Significance of Cardiac Troponin I Measurements in Myocardial Injury
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摘要 目的 探讨心肌肌钙蛋白Ⅰ (cTnI)对心肌损伤的诊断和鉴别诊断价值。方法 对 1 5例确诊急性心肌梗死 (AMI)和 1 5例诊断明确的单纯肌酸磷酸激酶 (CK)增高无心肌损伤患者同一份血样分别行cTnI和CK、肌酸磷酸激酶同功酶(CK MB)测定。结果 cTnI在AMI组阳性率为 1 0 0 % ,对照组阳性为 0 ,两组差异非常显著 (P <0 .0 0 1 )。CK MB在AMI阳性率为 93 3 % ,对照组阳性率为 80 % ,两组相比无显著差异。结论 cTnI对心肌损伤具有很重要的诊断价值。 Objective To investigate diagnostic significance of cardiac troponin I (cTnI) measurements in myocardial injury. Methods The levels of serum cTnI, CK, CK-MB were determined in 15 patients with actue myocardial infarction and 15 patients with elevated CK. Results The positive rate of cTnI is 100% in AMI group. That is 0 in control group. There were significant differences between two groups (P<0.001). The positive rate of CK-MB is 93.3% in AMI group. That is 80% in control group. There were no significant differences between two groups. Conclusion The present study suggests that serum cTnI measurements shows very importana diagnostic value for myocardial injury.
出处 《临床军医杂志》 CAS 2001年第3期31-32,共2页 Clinical Journal of Medical Officers
关键词 心肌肌钙蛋白Ⅰ 心肌损伤 诊断 cardiac troponin I myocardial injury test diagnostic
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参考文献4

  • 1ETIEVENT JP, CHOCRON S, TOUBIN G, et al. Use of cTnI as a marker of perioperative myocardial ischemis[J]. Ann Thorac Surg, 1995, 59: 1192.
  • 2TSUNG SH. Several conditions causing elevation of serum CK-MB and CK-BB[J]. Am J Clin Pathol, 1981, 75: 711.
  • 3ADAMS JE, BODOR GS, DAVILA-ROMAN VG, et al. Cardiac troponin I: a marker with high specificity for cardiac injury[J]. Circulation, 1993, 88:101.
  • 4vip TG, TUTER PG, LANDENSON JH, et al. Myocardial injury in critically ill patients[J]. JAMA, 1995, 274: 1672.

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