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肠球菌的耐药性分析 被引量:3

Analysis of Enterococcus spp. resistance to antibiotics
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摘要 目的 研究临床分离的肠球菌对常用抗生素的耐药性及肠球菌与感染性疾病的关系。方法 应用 VITEK全自动微生物分析仪对临床标本中分离的 88株肠球菌进行鉴定和药物敏感试验。结果 肠球菌对临床常用 9种抗生素耐药率以呋喃妥因及万古霉素最低 ,分别为 1.5 %、2 .3% ;其次为氨苄西林和青霉素G,分别为 2 1.3%、34 .1%。而对氯霉素、诺氟沙星、四环素及高浓度的庆大霉素、链霉素均呈一定程度耐药 ,耐药率都在 43%以上。结论 肠球菌对临床常用 9种抗生素以呋喃妥因及万古霉素最为敏感。本地区所流行菌株对青霉素 G仍有较高敏感率。高度耐氨基糖苷类的肠球菌已有相当比例。 Eighty eight clinical isolates of Enterococcus spp. in our hospital were collected and their resistance to antibiotics as well as the relationship between the pathogens and the incidence of infectious diseases were also investigated. The identification and the drug susceptibility tests were analyzed by VITEK automatic microbiology analytical instrument system. Rusults showed that the resistant rates of infections due to Enterococcus spp. to nitrofurantion and vancomycin were 1.5% and 2.3% respectively, followed by ampicillin (21.3%), penicillin G 34.1%; Chloramphenicol, norfloxacin, tetracycline, gentamicin (high concentration) and streptomycin showed moderate resistance, with average resistant rate higher than 43%. It was concluded that nitrofurantion and vancomycin were the most potent antibiotics among the nine commonly used drugs in our hospital. The epidemiological enterococcus infections in this region were still susceptible to penicillin G, but strains which were highly resistant to aminoglycosides were also present in certain extent. The most prevalent incidence diseases caused by Enterococcus spp. were urinary track infections.
出处 《中国抗生素杂志》 CAS CSCD 北大核心 2001年第5期380-381,共2页 Chinese Journal of Antibiotics
关键词 肠球菌 耐药性 氨基糖苷类 Enterococcus Drug resistance Aminoglycosides
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二级参考文献5

  • 1马俊春,上海医学检验杂志,1994年,9卷,60页
  • 2周俊春,中华医学检验杂志,1995年,18卷,164页
  • 3马俊春,中华医学检验杂志,1992年,15卷,33页
  • 4贺学英,中华医学检验杂志,1997年,268页
  • 5周惠平,中华医院感染学杂志,1995年,5卷,200页

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