摘要
目的 :研究幕上幕下占位性病变引起的颅内高压与颅底血管经颅多普勒 (transcranialDoppler,TCD)各参数之间的关系。方法 :兔随机分成幕上组和幕下组 ,硬膜外腔预置球囊 ,扩张造成急性颅内高压 ,每隔 15min扩张球囊一次 ,用TCD同时监测基底动脉 (basilarartery ,BA)、右侧的大脑中动脉 (rightmiddlecerebralartery ,rMCA)并记录TCD参数、颅内压 (intracranialpressure ,ICP)、体循环动脉压 (systemicarteralpressure ,SAP)。结果 :①正常BA的频谱形成态与MCA的频谱形态不同 ,呈高阻力、低血流的特征。②在球囊体积为 0 4ml,0 5ml水平处 ,幕上组的ICP比幕下组明显增高 (P <0 .0 5 )。③幕上组MCA的TCD参数与ICP的相关性比BA的TCD参数与ICP的相关性密切 ;幕下组 :BA的TCD参数与ICP的相关性比MCA的TCD参数与ICP的相关性要密切。结论 :①幕上或幕下占位性病变存在颅内压力梯度 ,颅内压监护探头应放在病变处或尽可能靠近病变。②利用TCD行无创性ICP监护时 。
Objective To evaluate the correlation between increased intracranial pressure in supratentorial, infratentorial and TCD parameters of basal arteries. Methods Sixteen New Zealand white rabbits were randomly divided into two groups: supratentorial group and infratentorial group. Intracranial pressures were raised after inflation of a preplaced epidural balloons. TCD parameters of the BA, rMCA were examined at intervals of 15 minutes after inflation of the balloon. ICP, ASP, HR, R were also recorded simultaneously. Results ①The normal spectra of BA were characterized by a high-risistance, low-flow waveform. ② At the 0.4ml, 0.5ml balloon volume level, ICP in supratentorial group was significantly increased than that in infratentorial group;③The correlation between ICP and MCA's TCD parameters were better than that between ICP and BA's TCD parameters in the supratentorial group. In the infratentorial group, the correlation between ICP and BA's TCD parameters were better than that between ICPs and MCA's TCD. Conclusions ①There are intracranial pressure gradients in mass lesions, so fibroptic probe should be placed at the place where the mass lesion takes place. ② To perform non-invasive ICP monitoring by TCD, the basal artery should be chosen according to the mass lesions.
出处
《湖南医科大学学报》
CSCD
北大核心
2001年第4期383-386,共4页
Bulletin of Hunan Medical University
基金
卫生部资助课题 (资助号 :98-1-113)
