摘要
目的 分析新生儿机械通气并发下呼吸道感染的易感因素、致病菌的变迁 ,以寻求防治措施。方法 1996～ 1999年行机械通气 1天以上的 133例患病新生儿按照胎龄、体重及插管时间分组 ,分析发生下呼吸道感染有无差异。所有病原学分析全部采取插管内采气道分泌物培养。结果 新生儿机械通气插管时间大于 3天 ,下呼吸道感染的发生率明显增高 ,低出生体重儿、早产儿其机械通气后下呼吸道感染的发生率和足月、正常出生体重儿比较 ,有升高的趋势 ,但统计学无显著意义。致病菌以克雷伯杆菌、大肠埃希菌、绿脓杆菌、不动杆菌为主。结论 临床上合理应用机械通气 ,及早撤机 ,根据致病菌的变化合理应用抗生素 ,能有效地预防及治疗新生儿因气管插管。
Objective To analyze the susceptible factors and the changes of the pathogen in infants with mechanic ventilation-associated lower re spiratory infection and find better method to avoid it.Methods 133 infants who were ventilated for at least one day in 199 6～1999 were divided into 2 groups according to gestational age,weight and venti l ation time and compare the infective morbidity in these groups.All the pathogen was proved by secretion culture.Results The infection morbidity was significantly higher in group v entilation time at least 3 days.The infection rate in groups of pre-term and lo w birth weight infants were higher than the full-term infant was and normal bir th weight groups,but the difference waint significant.Klebsialla,Escherechia col i,Pseudomonsa and Acinetobacter were the four main germs,but the rate of each ge rm was different in every year.Conclusion Using the ventilator reasonably,stopping it as soon as p ossible and using antibiotic according the germ culture are useful to prevent ve ntilation-associated lower respiratory infection.
出处
《中国实用儿科杂志》
CSCD
北大核心
2001年第9期546-548,共3页
Chinese Journal of Practical Pediatrics
关键词
新生儿
机械通气
下呼吸道感染
并发症
Infant Mechanic ventilation Lower respiratory tract infection
