摘要
观察了35例冠心病病人口服巯甲丙脯酸前后血浆载脂蛋白的变化。结果表明,口服巯甲丙脯酸后血浆载脂蛋白A_1,载脂蛋白A_1/载脂蛋白B_(100)显著增高(P<0.01,P<0.05),载脂蛋白B_(100)无明显变化(P>0.05)。提示巯甲丙脯酸可改变血浆载脂蛋白浓度,从而抑制动脉粥样硬化的发生和发展。
The serum apolipoprotein in 35 patients with coronary heart disease was examined before and after taking captopril. We found that after taking captopril, the content of APO A_1 and APOA_1/APO B_(100) were remarkably increased (P<0.01, P<0.05), while the content of APO B_(100) showed no significant change. These results indicates that captopril has an effect in preventing the occurrence and development of atherosclerosis.
出处
《青岛医学院学报》
1991年第4期327-329,共3页
Acta Academiae Medicinae Qingdao Universitatis
关键词
巯甲丙脯酸
载体蛋白类
冠心病
mercaptopropionic acid
carrier proteins
captopril
