摘要
目的 :了解并探讨老年高血压病 (HPE)血压昼夜节律改变与靶器官损害 (TOD)的关系及临床特点。方法 :对 12 6例 HPE患者和 84例非老年高血压病 (HPNE)患者进行 2 4小时动态血压监测 (ABPM) ,并比较其结果。结果 :HPE组昼夜节律异常发生率明显高于 HPNE组 (P<0 .0 1)。 HPE组昼夜节律异常者并发症发生率明显高于昼夜节律正常者 ,也明显高于 HPNE组昼夜节律异常或正常者 (P均 <0 .0 1)。HPE组昼夜节律异常者的心胸比值、QRS波振幅时间乘积及血肌酐水平明显大于其余各组 ,而肌酐清除率明显降低 (P均 <0 .0 1)。结论 :HPE昼夜节律的改变对 TOD的影响较 HPNE组更显著。对于 HPE患者 ,恢复其正常昼夜节律是治疗的关键。
Objective:To study relationship between abnormal circadian variation of blood pressure(BP) and target\|organ damage in elderly hypertension(HPE).Methods:Ambulatory BP monitoring was performed in 126 cases of HPE and 84 cases of nonelderly hypertension(HPNE).Results:The rate of abnormal BP circadian variation in the HPE was higher than those of HPNE group(P<001).The rate of complication in HPE with abnormal BP circadian variation was higher than those of HPE with normal BP circadian variation and HPNE(with normal or abnormal BP circadian variation),P<001 all.Conclusion:Influence of HPE with abnormal BP circadian variation on target\|organ damage is more than that in HPNE group.Recover BP circadian variation to normal is the key of therapy.
出处
《心血管康复医学杂志》
CAS
2001年第4期310-312,共3页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
动态血压监测
高血压
老年人
昼夜节律
靶器官
Ambulatory blood pressure monitoring
Hypertension
Elderly
Circadian variation
Target\|organ
