摘要
目的：概述丙型肝炎病毒核心蛋白的主要生物学功能。方法：查阅并参考国外近年 20多篇相关文献资料。结果：综述了丙型肝炎病毒核心蛋白 T、 B细胞表位及对细胞周期的影响。结论：核心蛋白是丙型肝炎病毒疫苗研究的靶区域，与病毒持续性感染、肝细胞肝癌的发生密切相关，对其深入研究有助于探讨丙型肝炎病毒的致病机制及其防治。
Objective:To generalize the biological function of hepatitis C Virus(HCV)core protein.Method:More than 20 current foreign literatures were read and reviewed.Results:There are some T and B cell epitopes on HCV core protein,and HCV core protein can affect cell cycle.Conclusions:HCV core protein was the target region of studying vaccine,related with persistent infection and hepatocarcinoma.The reviewed results are beneficial to study the HCV pathogenesis and therapy for hepatitis C.
出处
《大理医学院学报》
2001年第1期57-59,共3页
Journal of Dali Medical College
关键词
丙型肝炎病毒
核心抗原
表位
细胞周期
肝癌
Heaptitis C virus
Core antigen
Epitopes
Cell Cycle
Hepatocarcinoma
