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白癜风人群微量元素营养状况的临床流行病学分析 被引量:3

Investigation on Trace Element Level in Vitiligo
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摘要 目的:为进一步探讨微量元素的体内营养水平与白癜风发病、转归的因果关系。方法:以张家口医学院第一附属医院皮肤病专科门诊一年期间所筛查出的所有白癜风患者作为观察对象,进行毛发中铜、铁、锌等元素的测定分析。所得数据按不同年龄、不同病程、不同发段分组统计比较。结果:白癜风患病人群毛发中铜锌含量明显低于正常人群,且铜含量的降低随病程的延长而加重。结论:白癜风患病人群毛发中微量元素铜含量低于正常人群的现象,可能是疾病引起的体内代谢紊乱所造成的,建议临床不宜用补充铜元素来作为本病的治疗手段。 Objective:This investigation was to study trace elements level in vitiligo case.Methods:Objects of observation in the study were all screened from a hospital's demiatosis clinic during a year. To survey and analyze trace elements (copper, iron, zinc etc) in hair. Data were compared according to age, duration of disease and length of hair. Results: The level of copper and zinc in vitiligo case were lower than in normal population. Conclusion: It was possible that vitiligo might cause decompensation, the therapy of supplied trace elements (zine, copper,etc) should not work in treatment of vitiligo.
出处 《岭南皮肤性病科杂志》 2001年第2期70-72,共3页 Southern China Journal of Dermato-Venereology
基金 河北省2000年医学科研重点课题计划资助项目课题号2K065
关键词 白癜风 微量元素 临床流行病学 Vitiligo Trace element Copper Iron Zinc
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  • 1Soderbergh A, Rorsman F, Halonen M, et al. Autoantibodies against aromatic L - amino acid identifies a subgroup of patients with Addison. J Clin Endocrinol Metab, 2000, Jan: 85.
  • 2Iyengar B, Mendiratta PC. Cupricious and DOPA oxidese activity in melanocytes. Acta Morphol Hung: Institute of Pathology- ICMR, New Delhi, India. 1988. 36(1 - 2): 9 - 95.
  • 3张淑妍.白癜风患者123例毛发锌铜测定分析[J].岭南皮肤性病科杂志,1997,4(3):6-7. 被引量:5
  • 4Bruske K, Salfeld K. Zinc and its status in some dermatologic disease a statistical assessment. Z Hanker, 1987. 62 1:31-125 (suppl).

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