摘要
目的 :旨在进一步提高胃肠道肿瘤病人的生存率和生活质量 ,寻求新的安全有效的治疗方法。方法 :1995年 10月开始我们随机对胃肠道肿瘤病人在手术切除肿瘤后 ,术中对肿瘤淋巴引流区采用电子束照射 2 0～ 2 5Gy(31例 ) ,同期对照组 (71例 )仅行手术 ,两组术后均行MF +CF或口服氟脲嘧啶化疗 ,就安全性进行分析。结果 :术后伤口愈合情况和肠蠕动恢复同常规胃肠道肿瘤手术 (P >0 .0 5 ) ,手术时间比通常延长 2 0～ 30min ,实为放射治疗时间。术后复查血常规 ,也未发现白细胞总数或成分明显变化。两组病例均未发生术后出血、吻合口瘘、肠坏死等并发症。术后至 2 0 0 1年 2月其远期随访中未发现肠坏死、以及局部纤维化造成的胰腺功能不良或者肠粘连 ,也未发现术后局部复发。结论 :术中放疗本身是一种既经济、又安全有效的综合治疗措施。
Objective: It is the objective to raise the survival rate and quality of life in patient with gastric carcinoma or intestinal carcinoma. Methods: Since Oct 1995, in the operation, after resecting the gastric or intestines tumor, the area of lymph drain that gastric carcinoma or intestinal carcinoma were irradiated by the 6-14meV electron beam (DT: 20～25Gy)(31 cases). And the control group (71 cases) was operated only. All of cases were cured by chemotherapy of MF+CF after the operation. Its effect was analised. Results: There was no different between the two groups in wound healing and recovery of vermiculation after the operation ( P >0.05). Operation time with the group of introoperative radiotherapy was longer about 20-30 Min. than the control groups. There was no change of total and component of leucocyte after operation. Two groups did not happened complication after operation, such as bleeding, stoma fistula and bowel necrosis. There were the bowel necrosis, and pancreas malfunction & adhesion of intestine, and relapse after opration. Conclusions: Introoperative radiotherapy is a safety and operative therapy. There is active significance that introoperative radiotherapy is used in the patiens with gastric carcinoma or intestinal carcinoma.
出处
《中国临床医学》
2001年第4期352-354,共3页
Chinese Journal of Clinical Medicine
关键词
胃癌
大肠癌
手术中
放射治疗
安全性
外科手术
Gastric carcinoma Intestinal Carcinoma Introoperative radiotherapy Operative treatment Reliability
