摘要
目的 :探讨还原型谷胱甘肽 (GSH)对老年人急性心肌梗塞后 2周内左心室功能的影响。方法 :2 3例老年急性心梗患者随机分为两组 ,采用多普勒超声心动图观察 13例GSH治疗组 2周后左心室功能状况 ,并与对照组比较。结果 :GSH治疗组的心搏量 (SV)、心输出量 (CO)、心脏指数 (CI)、射血分数 (EF)及平均左室周边缩短率 (mVcf)均高于对照组 (P <0 0 5 ) ,但心室快速充盈期与心房收缩期血流速度比值 (E/A)两组间无显著性差异 (P >0 0 5 )。结论
Objective:To investigate the effect of reduced glutathione (GSH) on left heart function in elderly patients two weeks after acute myocardial infarction.Methods:Twenty-three cases of acute myocardial infarction ages of 65 or older were randomly divided into two groups.Thirteen patients were treated with GSH for 2 weeks immediately after admission,and 10 were the control.Left heart function of all the patients were assessed by two dimensional echocardiography and Doppler.Results:The stroke volume (SV),cardiac output (CO),cardiac index (CI),ejection fraction (EF)and mVcf were significantly increased in GSH treated group (all P <0 05) whereas the ratio of E/A showed no significant change among the two groups ( P >0 05).Conclusions:Treatment with reduced glutathione (GSH) in elderly patients with acute myocardial infarction has beneficial effect on left ventricular function.
出处
《华西医学》
CAS
2001年第3期291-292,共2页
West China Medical Journal
