摘要
本文报导了本实验条体下,利用pH电位法对组氨酸(His)与铜、锌二元配合物体系及黄芩甙(H_3B)、组氨酸与铜、锌三元配合物体系的研究结果。利用计算机SCOGS_2程序处理实验数据,建立了各体系的最佳化学模型,确定了各体系在实验条件下的有关常数,并给出了各体系的配位物种分布图。结果表明在组氨酸与铜、锌二元配合物体系中主要配位物种有:His-Cu;Gu(His)^+,Cu(His)_2,Cu(His)_2 H,Cu(His)(OH);His—Zn:Zn(His)^+,Zn(His)_2,Zn(His)_2H^+。在黄芩甙、组氨酸与铜、锌的混配配合物种主要是:M(His)(B)^(2-),M(His)(B)H^-,且有较强的稳定性。
The ternary complexes stibility constents of Baicalin、Histidine with Cu^(2+) Zn^(2+) were determined by potentiometric titration at 37±0.1℃ in 16%(V/V) dioxane-water mixed solvent in presence of 0.15M/dm^3 NaCl, potentiometric data were treated with SCOGS_2 program. The composition of complex species were ascertained in the complex equilibriums by selection of different chemical models. The △logK values indicate that the complexes with mixed ligands were obviously more stable than the simple binary systems. Distribution curves of the complex species have also been given. At physiological pH regiol these complexes, existed mainly in the form of the ternary compl xes. Meanwnile in this paper the experimental results is discussed.
出处
《宁夏大学学报（自然科学版）》
CAS
1991年第4期47-52,共6页
Journal of Ningxia University(Natural Science Edition)
关键词
黄芩甙
组氨酸
铜
锌
络合物
中药
Baicalin, Histidine, pH-pc entiometric titraticn, baalncing modelitng
