摘要
目的 :探讨影响 IGT (糖耐量低减 )者转归的重要因素。方法 :以普查出的 IGT者作为研究对象 ,追踪观察5年后 ,复查血糖 ,将获得的资料作非条件 logistic回归分析。结果 :对 118例 IGT者经 5年追踪观察 ,共随访到 85例 ,其中 DM(糖尿病病人 )的年转换率为 3.5 %,转为 NGT (正常者 )的年转换率为 2 3.5 %。研究结果表明年龄 (OR=1.0 70 ,P<0 .0 5 ) ,首次空腹血糖 (OR=2 .2 13,P<0 .0 5 )在 IGT者转归中起着重要作用。结论 :首次空腹血糖水平可作为预测 IGT转归的指标。
Objective:To explore the influential factors on the development of IGT.Method:118 individuals with IGT were identified by population-based screening.Then a follow-up study was carried out to observe the development of IGT and to evaluate its influential factors for five years.During this period,the serum glucose level was measured at regular intervals.Non-conditional logistic regression model was employed to analyse the data.Result:Among 118 individuals with IGT,85 persons remained in the cohort at the end of the five-year follow-up.Yearly,3.5% of them worsened to diabetes mellitus,and 23.5% of them returned to normal.The result showed that age and baseline fasting serum glucose level were the major predictors of IGT worsening to diabetes.The ORs of them were 1.070(P<0.05) and 2.313(P<0.05) respectively.Conclusion:Baseling fasting serum glucose level could be employed as a predictor of IGT worsening to diabetes mellitus.
出处
《现代预防医学》
CAS
2001年第4期421-422,共2页
Modern Preventive Medicine
