摘要
总结19例晚发性维生索K缺乏,所有病例均有颅内出血、呕吐、烦躁、惊厥、前囱隆起。其中16例母乳喂养,实验室发现凝血时间延长,脑脊液检查有皱缩红细胞和吞噬含铁血黄素的白细胞。讨论了婴儿维生素K缺乏的诊断和治疗,认为早期维生素K的使用是关键。
We report 19 infants with late Vitamin K deficiency. All cases hadintracrtanial hemorrhage which led to vomiting,restlessness,seizure and bulging of fontanelle.Sixteen of them was breast-fed.Labortory tests showed prolonged coagalation time, prothrombintime and kaolin partial thromboplastin time.CSF had shrivelled RBC and hemosiderin inleukocytes.Its mortality was 26.3%, and 3 of them have permanent sequelae.The diagnosis andtreatment of late Vitamin K deficiency in infants were discussed, and early administrationof Vitamin K was recommended.
关键词
维生素K
颅内出血
婴儿
Vitamin K deficiency
intracranial hemorrhage
infant
