摘要
对29例糖尿病人行基础状态血生长激素(GH)测定,其中9例升高。此9例中7例有慢性并发症,而20例GH正常者仅4例有慢性并发症(P<0.05)。对9例血GH升高者行阿托品试验(1mg静注),结果表明:注射阿托品后30′血GH即见下降,40′、60′、75′各时相GH仍保持下降趋势,至90′下降最明显,与0′时相比较有显著差异(P<0.05)。试验前后血糖值无明显变化。本试验表明:阿托品具有抑制糖尿病高GH血症的作用,这可能有助于糖尿病慢性并发症,尤其是血管并发症的防治,值得临床进一步观察。
Abstract The authors observed the basal level of se(?)m grewth hormone concentrations (GH) in 29(?) diabetics. Nine cases had an elevation of serum GH, among them seven cases had chronic diabetic complications. In the 20 diabetics with normal GH level only four cases had chronic diabetic complications. Atropine test (1 mg iv) were done on 9 diabetics with elevated serum GH, after injection of atropine, the serum GH levels at 40, 60, 75, 90 minutes were markedly decreased (especially at 90min) (P<0. 05). The blood glucose levels did not change significantly before and after the atropine test. There were no side effects during the test. The test indicats that atropin can inhibit elevetion of serum growth hormone in chronic diabetics. It may be useful in the management of diabetic chronic complications.
关键词
糖尿病
高生长激素
血症
阿托品
diabetes mellitus
hypergrowthhormonemia
atropin
