摘要
对1日龄5个品种鸡颈静脉接种禽成髓细胞增殖病病毒(AMV)BAI-A/株,并进行血液、组织病理及超微结构变化的研究和不同品种雏鸡易感性的比较。结果表明,该病最显著特征是血液学变化,血液及骨髓中出现大量成髓细胞。剖检可见肝、脾显著肿大,出血。光镜检查,病变几乎波及所有器官,成髓细胞在血管内外广泛聚集。电镜观察,成髓细胞核呈多形性,核仁大而明显,核内常染色质占优势。胞浆富有多聚核糖体。5个品种鸡以AA鸡最易感,AV鸡次之,罗斯、星布罗和京白鸡易感性低。
One-day-old chickens of 5 strains were injected intravenously with AMV BAI-A strain. Strain AA and AV were more susceptible to the disease than other strains. The most typical change of myeloblastosis was a great number of myeloblasts in blood smear, which is valuable in diagnosis. Myeloblasts were of large size, with high N/C ratio, and slightly basophilie cytoplasm figures. Histopathological examinations revealed massive intravascular and extravascular accumulation of myeloblasts in most organs and degeneration and necrosis of parenchymal cells. The ultrastructure of myeloblasts, showed large, evident and plemorphie nuclei with prominent euchromatin, and abundant polyribosomes in cytoplasm. AMV was observed in the ultrathin sections of infected tissue.
出处
《南京农业大学学报》
CAS
CSCD
北大核心
1991年第2期79-82,共4页
Journal of Nanjing Agricultural University
基金
高校博士点科学研究基金
关键词
禽成髓细胞
增殖病
病理学
肿瘤病
avian myeloblastosis
histopathology
ultrastructure
