摘要
用核酸凝胶电泳法对1985—1986年山东省十地市的318份婴幼儿急性腹泻粪便标本中测出的170份HRV阳性标本作了RNA电泳型分析,发现3个地区为HRVI亚群流行,3个地区为HRVⅡ亚群流行,4个地区为两亚群共同流行,共检出差异电泳型34个,其中14个属长RNA电泳型,20个属短RNA电泳型。在一个地区虽有多个差异电泳型毒株流行,但仅有其中的1—2个占流行优势。在两亚群毒株共同流行区,检出的差异电泳型特别多。本文并对HRV RNA电泳型多形性的原因及意义进行了讨论。
Using the PAGE method, we analysed the electrophoretic types of RNA rotavirus obtained from 170 stool samples with infantile diarrhea from ten cities in Shandao from 1985—1986, In 3 cities subgroup Ⅰ rotavirus was found to be the main etiologic agent, subgroup Ⅱ in other 3 cities and both subgroups were found prevailing in the rest cites. Among 34 different electrophoretic typs observed, 14 belong to subgroup Ⅰ and 20 to subgroup Ⅱ。In the cities with two subgroups co-prevailing, there were far more electrophoretic types found than in the cities with only one subgroup. The significance of the genetic diversity of the rotavirus genome is also discussed.
出处
《病毒学杂志》
CSCD
1989年第4期359-364,共6页
关键词
轮状病毒
流行病学
电泳图形
Rotavirus
Molecular epidemiology
Electrophoretic pattern