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脾下极动脉栓塞治疗脾功能亢进的动物实验研究 被引量:11

Embolization of Splenic Lower Pole Artery for Hypersplenism: An Experimental Study
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摘要 目的 研究脾下极动脉栓塞 (SLPAE)技术的改进及其治疗效果。方法 使用不同插管技术和栓塞物对 3只犬行部分性脾动脉栓塞 ,观察术后反应、外周血象和组织病理改变。结果  3种方法栓塞后均有血小板计数显著增高及大网膜对脾下极包裹粘连。脾下极动脉栓塞后仅有较轻不良反应。鱼肝油酸钠脾下极栓塞产生完全凝固性坏死 ,栓塞区无残存脾组织。结论 脾下极动脉栓塞不良反应少 ,抑制脾功能的效果与传统方法相似。应用微导管和液态硬化剂栓塞更为安全可靠。 Purpose To improve the method of splenic lower pole artery embolization(SLPAE) and study the result. Methods Three dogs received partial splenic embolization by using different catheterization and embolizing materials. Post embolization reaction including general state, peripheral hemogram and pathological changes were observed. Results Marked increase of platelet and omentum surrounding to the lower pole of spleen were seen in all the 3 dogs. SLPAE only caused slight side effects. Sodium morrhuate gave rise to a complete coagulation necrosis to the embolized area. Conclusion With less untoward effect, SLPAE is as effective as conventional partial splenic embolization in suppress splenic function. Using microcatheter and liquid embolizing material will make the procedure safer and more effective.
出处 《中国医学影像技术》 CSCD 2001年第9期890-892,共3页 Chinese Journal of Medical Imaging Technology
关键词 脾动脉 栓塞 脾功能亢进 治疗 Splenic artery Embolization Hypersplenism
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