摘要
目的 探讨亲水性丙烯酸酯折叠式人工晶状体 (intraocularlens ,IOL)的临床疗效。方法将 2 14只眼随机分为两组 ,试验组 (114只眼 )植入亲水性丙烯酸酯折叠式IOL ;对照组 (10 0只眼 )植入聚甲基丙烯酸甲酯 (polymethylmethacrylate ,PMMA)一体型IOL。观察手术前、后视力 ,角膜曲率和角膜内皮细胞密度的变化。术后 3个月散大瞳孔观察 119只眼IOL的位置和晶状体后囊膜的混浊情况。对两组结果进行统计学分析。结果 术后早期视力、3个月后手术性散光度数、晶状体后囊膜混浊的发生率、IOL位置试验组均优于对照组 ,差异有显著性 (P <0 0 5 ) ;术后 3个月角膜内皮细胞的损失率和矫正视力两组比较 ,差异无显著性 (P >0 0 5 )。结论 亲水性丙烯酸酯折叠式IOL生物相容性好 ,术中便于植入及固定 ,术后炎性反应轻、恢复快 ,临床应用效果满意。
Objective To investigate the therapeutic effects of hydrophilic acrylic foldable lens implantation. Methods This prospective randomized placebo-controlled study comprised 214 eyes of 190 patients after phacoemulsification. The hydrophilic acrylic foldable lens was implanted in group 1 (114 eyes), and the PMMA intraocular lens (IOL) implanted in the control group 2 (100 eyes). Within the 3-6 month follow-up period, the changes of visual acuity, corneal astigmatism and endothelial cells, the location of IOL and the degree of posterior capsular opaqueness postoperatively between the two groups were compared. Results The visual acuity of group 1 was significantly better than that of group 2 within 3 days postoperatively (P<0.05), but there was no statistically significant difference after 3 months. The surgically induced astigmatism, incidents of posterior capsular opaqueness and subluxation of IOL of group 1 were significantly lower than that of group 2 after 3 months postoperatively (P<0.05). The comparison of the endothelial cell loss ratio between the two groups was not significantly different (P>0.05). Conclusion The hydrophilic acrylic foldable IOL is easy to handle during implantation, highly biocompatible in the eyes, with less postoperative inflammatory reactions and shorter recovery period, and may provide satisfactory therapeutic effects.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2001年第6期431-433,共3页
Chinese Journal of Ophthalmology
